Rainbow Six Siege’s North America League Stage 2 returns Thursday, September 18 with our top betting tips for five key matchups.
Rainbow Six Siege’s North America League Stage 2 returns Thursday, September 18 with our top betting tips for five key matchups.

Rainbow Six Siege North America League 2025 Stage 2 returns on Thursday, September 18, with five best-of-one matches that could shake up the standings.
Rainbow Six Siege fans can look forward to marquee teams such as Spacestation Gaming, Cloud9, DarkZero, Wildcard and Shopify Rebellion taking on hungry challengers aiming to pull off upsets.
Here’s how Friday’s matches line up with our top Rainbow Six Siege betting tips with the top esports betting sites.
Best Odds: Spacestation Gaming -714.29 at BetOnline | Team Cruelty +400 at SportsBetting
When: Thursday, September 18, 2025 | 16:00 ET (UTC-4)
Watch Live: Twitch
Spacestation Gaming are coming off a dominant 7-2 win over ENVY and remain one of the most consistent teams in North America League play. Their experience from past titles and structured approach has translated to steady results in Stage 2, with clean executes and disciplined defence rounds putting them in control of most maps.
Team Cruelty have yet to find momentum at this level, opening Stage 2 with heavy defeats to ENVY, Oxygen and DarkZero. While the Mexican side can generate bursts of aggression, their lack of cohesion and late-round composure has left them vulnerable to sweeps against higher-ranked opposition.
Tip: Back Spacestation Gaming -4.5 rounds — their organisation and map discipline should be too much for a rebuilding Cruelty roster.
Best Odds: Cloud9 -175.44 at BetOnline | STANDBY LFO +125 at SportsBetting
When: Thursday, September 18, 2025 | 17:00 ET (UTC-4)
Watch Live: Twitch
Cloud9 have been inconsistent across Stage 2 but are coming off a confidence-building 7-0 sweep of Team Cruelty. Their structured play on defence and faster executes on attack have looked sharper since the addition of Hat, and they’ll look to build momentum against a struggling opponent.
STANDBY LFO remain winless in Stage 2 after close losses to ENVY and Spacestation Gaming. The newly acquired roster has shown moments of resilience but continues to falter in late-round situations and objective play, making it difficult to close out maps.
Tip: Back Cloud9 -2.5 rounds — their recent clean sheet and stronger coordination give them the upper hand over an LFO side still finding its feet.
Best Odds: DarkZero -227.27 at BetOnline | Oxygen Esports +162 at SportsBetting
When: Thursday, September 18, 2025 | 18:00 ET (UTC-4)
Watch Live: Twitch
DarkZero enter this matchup looking to stabilise their Stage 2 campaign after a mixed start. They’ve already notched solid wins over Team Cruelty and Cloud9, but narrow losses to Shopify Rebellion and M80 highlight issues with consistency in closing maps. Their experience at the highest level still makes them a dangerous opponent, especially in high-pressure rounds.
Oxygen Esports are riding a three-match win streak over Team Cruelty, Spacestation and Wildcard, signalling a steady upswing in form after a slow Stage 2 start. Their objective play and adaptability have been improving each match, giving them a realistic chance of an upset if they maintain composure late in rounds.
Tip: Back DarkZero -2.5 rounds @1.83 — their veteran core and stronger defensive structure should edge out Oxygen’s momentum in a tight contest.
Best Odds: Wildcard -188.68 at BetOnline | ENVY +137 at SportsBetting
When: Thursday, September 18, 2025 | 19:00 ET (UTC-4)
Watch Live: Twitch
Wildcard’s Stage 2 campaign has been a rollercoaster, mixing strong wins over Spacestation and steady performances on structured maps with narrow losses to M80 and Oxygen. Their fundamentals and map control remain among the best in the league’s middle pack, but lapses in late-round execution have cost them points.
ENVY are punching above expectations in Stage 2 with wins over Cloud9, LFO and Team Cruelty showing clear improvement from their debut season. They’ve been aggressive on entry and efficient on defense, yet a heavy loss to Spacestation highlighted vulnerabilities when facing more polished sides.
Tip: Back Wildcard -2.5 rounds — their superior map control and experience should prevail against an ENVY team still adjusting to higher-tier opposition.
Best Odds: Shopify Rebellion -151.52 at BetOnline | M80 +110 at SportsBetting
When: Thursday, September 18, 2025 | 20:00 ET (UTC-4)
Watch Live: Twitch
Shopify Rebellion have been the form team of Stage 2, winning four straight matches including narrow thrillers over DarkZero and Wildcard. Their structure and clutch play in overtime rounds have been decisive, and they’re proving difficult to break down on defense-heavy maps.
M80 are quietly building momentum with four consecutive victories of their own, highlighted by an 8–6 win over Wildcard and a strong showing against DarkZero. Their aggressive style has been more measured this stage, giving them better late-round execution and a balanced attack across all maps.
Tip: Back Shopify Rebellion -1.5 rounds — their tighter map control and ability to edge out close games should be enough to halt M80’s surge.